Scientific Image Gallery
Welcome to our Scientific Image Gallery. Here you can find real-life examples of cell images, mostly (but not only) from peripheral blood films, that illustrate typical morphologic characteristics pointing to specific conditions or disorders. This constitutes their diagnostic value.
Click on an image to enlarge it and display a short description.
Hairy cell from a hairy cell leukaemia. Typical are the monocytic type nuclei with loose chromatin, and the grey-blue, heterogeneous cytoplasm. The hairy protrusions may be missing in some cases.
<p>Hairy cell from a hairy cell leukaemia. Typical are the monocytic type nuclei with loose chromatin, and the grey-blue, heterogeneous cytoplasm. The hairy protrusions may be missing in some cases.</p>
Peripheral blood (May-Grünwald-Giemsa stain) of a patient with hairy cell leukaemia. A typical hairy cell (->) can easily be distinguished from a normal lymphocyte (lower right).
<p>Peripheral blood (May-Grünwald-Giemsa stain) of a patient with hairy cell leukaemia. A typical hairy cell (->) can easily be distinguished from a normal lymphocyte (lower right).</p>
Hairy cell leukaemia-variant (HCL-V).
<p>Hairy cell leukaemia-variant (HCL-V).</p>
This 'hairy' lymphocyte comes from a person suffering from an active infection (without any malignant disease). The granula identify it as a T or an NK cell.
<p>This 'hairy' lymphocyte comes from a person suffering from an active infection (without any malignant disease). The granula identify it as a T or an NK cell.</p>
Reticulocyte staining. Characteristic HbH cell in a case of α-thalassaemia. Today, blood films are no longer investigated for HbH cells. Instead,
α-thalassaemias are diagnosed by molecular genetic tests.
<p>Reticulocyte staining. Characteristic HbH cell in a case of α-thalassaemia. Today, blood films are no longer investigated for HbH cells. Instead, </p> <p>α-thalassaemias are diagnosed by molecular genetic tests.</p>
A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML.
<p>A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML. </p>
Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes.
<p>Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes. </p>
Bone marrow histology (Giemsa stain) of a patient showing an infiltrating Hodgkin's lymphoma on the left side. On the right side normal haematopoietic tissue can be seen.
<p>Bone marrow histology (Giemsa stain) of a patient showing an infiltrating Hodgkin's lymphoma on the left side. On the right side normal haematopoietic tissue can be seen.</p>
Howell-Jolly bodies in the cell adjacent to the granulocyte, spherocytes, polychromasia, and a single erythroblast in a case of auto-immune haemolytic anaemia (AIHA). (Howell-Jolly bodies are DNA remnants. Polychromatic cells still contain RNA.)
<p>Howell-Jolly bodies in the cell adjacent to the granulocyte, spherocytes, polychromasia, and a single erythroblast in a case of auto-immune haemolytic anaemia (AIHA). (Howell-Jolly bodies are DNA remnants. Polychromatic cells still contain RNA.)</p>